| 2022-05-01 15:00:0001/05/2022 | Lyra-Lierse  | 2 - 1 |  Londerzeel |
| 2022-04-24 15:00:0024/04/2022 | Hoogstraten  | 1 - 1 | Lyra-Lierse |
| 2022-04-17 14:30:0017/04/2022 | Wijgmaal  | 1 - 0 | Lyra-Lierse |
| 2022-04-09 20:00:0009/04/2022 | Lyra-Lierse | 3 - 0 |  Berchem |
| 2022-04-03 15:00:0003/04/2022 | Pepingen-Halle  | 1 - 2 | Lyra-Lierse |
| 2022-03-26 20:00:0026/03/2022 | Lyra-Lierse | 0 - 2 |  Bocholt |
| 2022-03-19 20:00:0019/03/2022 | Lyra-Lierse | 1 - 2 |  Hades |
| 2022-03-13 15:00:0013/03/2022 | Diegem  | 1 - 2 | Lyra-Lierse |
| 2022-03-05 20:00:0005/03/2022 | Lyra-Lierse | 0 - 2 |  Belisia |
| 2022-02-26 20:00:0026/02/2022 | Lyra-Lierse | 3 - 1 |  Hasselt |
| 2022-02-23 20:30:0023/02/2022 | Cappellen  | 0 - 0 | Lyra-Lierse |
| 2022-02-19 20:00:0019/02/2022 | Tongeren  | 1 - 2 | Lyra-Lierse |
| 2022-02-12 20:00:0012/02/2022 | Lyra-Lierse | 2 - 2 |  City Pirates |
| 2022-02-06 15:00:0006/02/2022 | Aalst  | 0 - 2 | Lyra-Lierse |
| 2022-01-29 20:00:0029/01/2022 | Lyra-Lierse | 0 - 1 |  Houtvenne |
| 2021-12-11 19:30:0011/12/2021 | Londerzeel | 4 - 1 | Lyra-Lierse |
| 2021-12-04 20:00:0004/12/2021 | Lyra-Lierse | 1 - 0 | Hoogstraten |
| 2021-11-27 20:00:0027/11/2021 | Berchem | 0 - 0 | Lyra-Lierse |
| 2021-11-20 20:00:0020/11/2021 | Lyra-Lierse | 5 - 2 | Pepingen-Halle |
| 2021-11-14 15:00:0014/11/2021 | Bocholt | 1 - 0 | Lyra-Lierse |
| 2021-11-07 14:30:0007/11/2021 | Hades | 0 - 4 | Lyra-Lierse |
| 2021-10-30 20:00:0030/10/2021 | Lyra-Lierse | 3 - 1 | Diegem |
| 2021-10-24 15:00:0024/10/2021 | Belisia | 0 - 2 | Lyra-Lierse |
| 2021-10-16 20:00:0016/10/2021 | Lyra-Lierse | 0 - 0 | Tongeren |
| 2021-10-09 20:00:0009/10/2021 | City Pirates | 0 - 2 | Lyra-Lierse |
| 2021-10-02 20:00:0002/10/2021 | Lyra-Lierse | 3 - 1 | Aalst |
| 2021-09-25 20:00:0025/09/2021 | Houtvenne | 1 - 3 | Lyra-Lierse |
| 2021-09-18 20:00:0018/09/2021 | Lyra-Lierse | 3 - 1 | Wijgmaal |
| 2021-09-11 20:00:0011/09/2021 | Hasselt | 0 - 3 | Lyra-Lierse |
| 2021-09-04 20:00:0004/09/2021 | Lyra-Lierse | 2 - 2 | Cappellen |
| 2020-10-11 15:00:0011/10/2020 | Berchem | 1 - 1 | Lyra-Lierse |
| 2020-10-03 20:00:0003/10/2020 | Lyra-Lierse | 3 - 0 | Cappellen |
| 2020-09-26 20:00:0026/09/2020 | Lyra-Lierse | 2 - 1 | Belisia |
| 2020-09-23 20:30:0023/09/2020 | Hasselt | 2 - 1 | Lyra-Lierse |
